Siemens Healthineers and NUH Launch Research for Liver Diagnostics

Siemens Healthineers and the National University Hospital (NUH) in Singapore have initiated a significant research collaboration aimed at improving diagnostic methods for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). This condition affects nearly 40% of adults in Singapore, a figure that surpasses the global average of 30.05%. The partnership seeks to address the rising prevalence of MASLD, which has become the leading cause of chronic liver disease worldwide.

The collaboration reflects a growing concern over the increasing rates of obesity and sedentary lifestyles contributing to metabolic conditions in Singapore. This trend underscores the urgent need for more efficient and patient-friendly diagnostic solutions in liver care. The research will be spearheaded by Associate Professor Dan Yock Young, a Senior Consultant in the Division of Gastroenterology and Hepatology at NUH and an Associate Professor at the Yong Loo Lin School of Medicine, National University of Singapore. His extensive expertise in liver disease research positions the project for success.

Innovative Diagnostic Technologies

The research initiative will focus on evaluating Siemens Healthineers’ advanced ultrasound technologies: Ultrasound-Derived Fat Fraction (UDFF) and Auto Point Shear Wave Elastography (Auto pSWE). These non-invasive tools allow for simultaneous measurement of liver fat and stiffness, presenting a safer and more cost-effective alternative to traditional methods such as MRI scans and invasive biopsies. Early detection and effective monitoring through these technologies could significantly enhance the management of liver diseases in the region.

According to Vy Tran, President of Asia-Pacific Japan at Siemens Healthineers, the collaboration aims to transform liver care. “Together with NUH, led by Associate Professor Dan Yock Young, we will study how advanced ultrasound technologies can transform liver care by offering a cost-effective alternative to invasive biopsy or high-cost imaging,” Tran stated. The goal is to make these innovative ultrasound technologies accessible not only in tertiary hospitals but also at polyclinics, aiming for earlier detection and intervention for patients.

Tackling a Silent Epidemic

This partnership is a crucial step in addressing MASLD, which is increasingly recognized as a major health issue in Singapore. “At NUH, we combine deep clinical expertise in liver and metabolic health, backed by strong translational research,” noted Associate Professor Young. “By working with partners such as Siemens Healthineers, we are well positioned to pioneer new approaches to detect, treat, and prevent the disease, thereby helping more patients live healthier lives.”

The collaboration coincides with the upcoming opening of the National University Centre for Digestive Health in January 2026. This facility aims to enhance patient access to innovative diagnostic solutions, further solidifying Singapore’s position as a leader in medical research and healthcare.

Chaitanya Mehrotra, Head of Ultrasound for Asia Pacific at Siemens Healthineers, emphasized the importance of this initiative. “With nearly 40% of adults in Singapore affected, fatty liver disease is a silent epidemic we can no longer ignore. This collaboration reflects our shared responsibility to change that story,” Mehrotra stated. He expressed optimism that introducing ultrasound innovation into frontline care will empower physicians and provide patients with accurate diagnostics and hope for a healthier future.

This partnership leverages the clinical expertise of NUH alongside the technological innovations of Siemens Healthineers, aiming to create breakthroughs in healthcare that are sustainable and beneficial for all. As both organizations work together, they hope to advance medical innovation and improve patient care outcomes across the Asia Pacific region.